- #Should i get my health report from 23andme plus#
- #Should i get my health report from 23andme series#
#Should i get my health report from 23andme plus#
On the plus side, 23andMe provides clear explanations of what it does and doesn’t test for, and lists other factors that contribute to disease risk. It just means you don’t have the ones tested for. Getting a report of “variants not detected” doesn’t mean you don’t have any variants related to a particular medical condition. The problem is, the company tests only a small subset of all potential SNPs. And 23andMe has FDA approval to report on a few health conditions linked to specific genetic variants, such as celiac disease and macular degeneration. Still, the company can tell you interesting things about some physical and physiological traits, like cleft chins, dimples or the ability to taste bitter flavors.
It’s the genetic equivalent of spot-checking a few letters in each chapter of War and Peace and trying to decipher the plot. That may sound like a lot, but it’s only 0.01 percent of the 6 billion DNA letters in the human genome. For $199, 23andMe examines about 690,000 predetermined SNPs. SNPs, short for single nucleotide polymorphisms, are the spelling variations in DNA. 23andMeĢ3andMe uses the oldest technology, called SNP genotype testing. The company’s wellness reports explain the factors that contribute to conditions such as lactose intolerance and detail how the company arrived at its conclusions. 23andMe GENETIC INSIGHTS 23andMe analyzes genetic variants to tell customers about a variety of health risks and traits. Veritas also sent a copy of its report to my doctor. The company says the typical wait time is closer to 12 weeks. Because of a technical glitch, it took about seven months to get results from Veritas. Within a couple of months, 23andMe and Genos emailed to tell me my results were available online. I also opted to let each company use my DNA in research studies, which required an extra step of answering a questionnaire about myself. Sample prep was easy - register the kit’s number online, spit in a tube, mail in the sample. The kits all contained the same type of saliva-collection tubes. She said there was nothing in my personal health records or family history that would normally lead her to order a genetic test.
My doctor reluctantly agreed, but only because I was exploring DNA testing as part of my job. Food and Drug Administration limits the medical information the company can report. 23andMe doesn’t, and as a result, the U.S. Genos and Veritas both require a doctor to sign off on the test. The DNA-testing process starts off the same for all of the companies I tried: ordering a kit online.
#Should i get my health report from 23andme series#
This story is part of a multipart series on consumer genetic testing. Where these companies differ is in how much of the genome they assess and whether they look for only a limited set of known variants or can uncover new ones specific to an individual. Where most people have, say, a “G,” some might have an “A.” Most of these genetic variants are harmless, but some raise the risk for certain diseases. (I did ancestry testing, too you can read about my experiences with that in June.) These companies all analyze natural spelling variations in the string of letters that make up DNA. Is more better? Would an expensive test that deciphered my entire genetic instruction manual, or genome, reveal more about me than more limited tests? That’s what I wanted to find out.įor health testing, I sent spit samples to 23andMe, Genos and Veritas Genetics, three companies that represent the various levels of DNA testing available to consumers. What finally motivated me to send away my DNA in the mail was the fact that companies are now offering much more genetic information. Direct-to-consumer genetic testing first came on the market about a decade ago, but I resisted the temptation to see what health information is hidden in my DNA - until now.Īs a molecular biology writer, I’ve been skeptical that the field of genetics is mature enough to accurately predict health ( see related article).